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Iron-dextran

Iron-dextran
Iron-dextran structure
CAS No.
9004-66-4
Chemical Name:
Iron-dextran
Synonyms
b75;a100;INFeD;fenate;Dexfer;Idofer;imferon;imposil;iro-jex;polyfer
CBNumber:
CB9139534
Molecular Formula:
FeH2O4S
Formula Weight:
153.92348
MOL File:
9004-66-4.mol

Iron-dextran Properties

form 
solution
EWG's Food Scores
1
FDA UNII
95HR524N2M
Proposition 65 List
Iron Dextran Complex
EPA Substance Registry System
Iron dextran (9004-66-4)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H317-H350
Precautionary statements  P201-P280-P308+P313
Hazard Codes  Xn,T
Risk Statements  40-42/43-43-45
Safety Statements  23-26-36/37/39-45-36-36/37-53
WGK Germany  -
RTECS  NI2200000
Toxicity LD50 i.v. in mice: 2240 mg Fe/kg (Beliles)

Iron-dextran price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D8517 Iron–Dextran solution 9004-66-4 25ml $128 2019-12-02 Buy
Sigma-Aldrich D8517 Iron–Dextran solution 9004-66-4 100ml $335 2019-12-02 Buy

Iron-dextran Chemical Properties,Uses,Production

Description

Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)
Iron-Dextran is for the parenteral treatment of iron-deficiency anemia in humans and baby pigs. Can be used as a reagent.

Chemical Properties

Light to dark brown powder. Colloidal suspension of an iron-dextran complex in water. pH 5.2-6.5.

History

The therapeutic value of colloidal iron preparations was first reported in the 1950's by London and Twigg. Numerous attempts have been made to improve these iron preparations Thus dextran ([h] 0.05) is first heated with alkali, and is then neutralized in the presence of ferric chloride solution. Studies on this product have revealed that each particle consists of a central iron core, approximately 3nm diameter, surrounded by a dextran sheath of approximately 13nm diameter. The complex is visualized as a particle formed by a protective sheath of dextran attached by terminal metasaccharinic acid units to a b-FeOOH core. A solution of this complex containing 5% iron and 20% dextran (Imferon ™ ) is suitable for intramuscular and intravenous injection for treating iron deficiency anemia. The product is currently used widely for treating anemia in new-born piglets.
The use of these preparations has been re-examined in humans and a dramatic rise in hemoglobin was reported following intravenous infusion. The solution is best administered together with glucose solutions.

Uses

Hematinic.

brand name

Dexferrum (Luitpold); Infed (Wat son); Proferdex (New River).

Reactivity Profile

Iron-dextran is unstable at a pH of 5 and decomposes at 149-158° F. Iron-dextran may be sensitive to prolonged exposure to air.

Health Hazard

SYMPTOMS: The symptoms associated with exposure to Iron-dextran are headaches, vomiting, and dizziness.

Fire Hazard

Iron-dextran is combustible.

Carcinogenicity

Iron dextran complex is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Iron-dextran Preparation Products And Raw materials

Raw materials

Preparation Products


Iron-dextran Suppliers

Global( 134)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2474 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21827 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30043 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23977 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
hdzhl biotechnology co., ltd
86-13032617415
sales@luchibiology.com CHINA 1277 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6371 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23045 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35434 58

View Lastest Price from Iron-dextran manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Iron-dextran
9004-66-4
US $1.00 / KG 1G 98% 100KG career henan chemical co

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